TNF and sarcoidosis: In the Serbian sub-cohort (Table 2), the strongest association of acute onset in the single locus model was found for rs1800629 (=TNFA-308G/A), a well-known sarcoidosis risk SNP that is located in the TNF promoter region: the A-allele was significantly associated with acute onset of the disease with an OR of 2.19 and displayed the smallest p value in the regression analysis (p = 1.31 × 10−9). Moreover, one marker in the HLA-region showed a significant association, namely rs4143332 in the HLA-B gene region (p = 3.60 × 10−8; OR = 2.22).