We identified novel genetic associations for fever or sub-febrile temperatures with rs3024505 near IL10 (p = 0.005; OR = 33.65) in the North German sarcoidosis patients, rs2233409 near NFKBIA (p = 0.005; OR = 1.58) in the Serbian patients, and rs2071746 near HMOX1 (p = 0.0096; OR = 0.24) in patients from Central Germany. The gene discussed is HMOX1; the disease is sarcoidosis.