Intravenous insulin therapy is recommended to avoid blood glucose level above 150 mg.dl− 1 (8.2 mmol.l− 1) and below 100 mg.dl− 1 (5.5 mmol.l− 1) after cardiac surgery since intra and postoperative hyperglycemia was reported to increase postoperative morbidity and mortality [25, 26]. The gene discussed is INS; the disease is Hyperglycemia.