Moreover, serum endocan level was reported to be overexpressed in patients with stress hyperglycemia having acute ST-segment elevation myocardial infarction (STEMI) [29] and to be higher in diabetic patients with acute STEMI compared to newly diagnosed, untreated and uncomplicated type 2 diabetes mellitus patients [30]. This evidence concerns the gene ESM1 and ST Elevation Myocardial Infarction.