The highest TyG index quartile had a higher proportion of patients with hypertension, diabetes and antidiabetic agent usage (P < 0.05); higher BMI, SBP, DBP, Hb, Hb1Ac, FBG, TG, TC, LDL-C and VLDL-C levels (P < 0.05); and lower HDL-C levels (P < 0.05). The gene discussed is GSTM1; the disease is Hypertension.