PCSK9 and myocardial infarction: Results of a prospective cohort analysis including individuals from the population-based UK Biobank and from 2 large international clinical trials, FOURIER (Further Cardiovascular Outcomes Research with PCSK9 Inhibition in Subjects with Elevated Risk) and IMPROVE-IT (IMProved Reduction of Outcomes: Vytorin Efficacy International Trial), concluded that risk of myocardial infarction was best captured by the number of apoB-containing lipoproteins [52].