PCSK9 and type 2 diabetes mellitus: To further explore whether complications associated to T2DM affected the circulating levels of PCSK9, an ANCOVA test, followed by Tukey’s post-hoc comparisons, was computed after adjustment for age, sex, HbA1c, and the presence of previous MACE, atherosclerotic vascular disease, nephropathy, neuropathy and retinopathy.