SPEN and adrenal cortex carcinoma: The results of univariate Cox regression analyses indicated that SPEN expression only notably affected the OS in KIRC (Supplementary Fig. 1A), the DSS in KIRC and LUSC (Supplementary Fig. 1B), the PFS in ACC, KIRC, LIHC, and LUSC (Supplementary Fig. 1C) and the DFS in ACC (Supplementary Fig. 1D).