In addition, the number of Iba1-positive cells activated increased from 3 h to 3 days (55.20 ± 8.04 vs 0.00 ± 0.00; P < 0.001; Fig. 2D) and the intensity levels of GFAP were induced at 3 days (19.49 ± 2.76 vs 4.09 ± 1.56; P < 0.001; Fig. 2E) around hematoma after ICH compared with the sham group. The gene discussed is AIF1; the disease is hematoma.