Further investigation is required to evaluate the potential link between BSN, GRIN2A, H2AFX, LEO1, NCOR1, NRXN3, PLCB1, POC5, PRRT2, SCN2A, SPI1, STX1B, UBXN7, VCL, YWHAZ, and obesity. The gene discussed is H2AX; the disease is obesity due to melanocortin 4 receptor deficiency.