Among these genes, YTHDF3, YTHDC2, RNMT, METTL5, IGFBP3, and TRMT10C were upregulated in both NAFL and NASH liver tissues, while IGFBP1 expression was downregulated, in agreement with previous reports [34] (Suppl. Here, IGFBP1 is linked to metabolic dysfunction-associated steatohepatitis.