In univariate analysis of high TBS group (n = 299, Table 5), older age, positive HBsAg and anti-HCV, lower albumin level, higher bilirubin level, higher creatinine level, thrombocytopenia, higher INR of PT, AFP > 200 ng/mL, performance status 2–4, ALBI grade 2–3, vascular invasion, and TACE were linked with a shortened survival. This evidence concerns the gene AFP and Thrombocytopenia.