The TCGA pan-cancer analysis revealed upregulated LINC00880 expression across most types of cancers, including head and neck squamous cell carcinoma (HNSC), liver hepatocellular carcinoma (LIHC), kidney renal clear cell carcinoma (KIRC), glioblastoma (GBM), and LUAD (Fig. 1B). The gene discussed is LINC00880; the disease is cancer.