The DNA sequencing data revealed mutations in tumor suppressor genes such as MYO18B, CTNN2, and NAV392,93 and in genes related to adhesion, invasiveness, and survival including CDH23, HMCN1, OBSCN, ADGRL2, and MYEOV94,95 in tumor samples at acquired resistance. The gene discussed is MYO18B; the disease is neoplasm.