Strikingly, 4T1/Ctrl mice displayed much shrinking eWAT and iWAT morphology than tumour-free or 4T1/Rab27a KO mice and lower eWAT, iWAT, gastrocnemius (GA) and tibial anterior (TA) weight were detected (Supplementary Fig. 1e, f). Here, RAB27A is linked to neoplasm.