Cystic Fibrosis (CF) is a monogenic disease due to mutations in the CF transmembrane conductance regulator (CFTR) gene [1], which regulates ion transport, that impair lung mucociliary clearance and result in pathological triad hallmarks of CF, i.e., chronic airway mucus build-up, sustained inflammation, and microbe trapping leading to parenchyma epithelial cell destruction. Here, CFTR is linked to cystic fibrosis.