VSH-02 was a 6 year old (at time of treatment), neutered male, Bichon mix with a history of hypothyroidism, insulin dependent T1DM (6 months duration at time of treatment–with preexisting islet autoantibodies confirmed by FACS for anti-IC serum IgG), and elevated Alkaline Phosphatase, ALT, Cholesterol, Triglycerides and hyperkalemia prior to treatment. This evidence concerns the gene GPT and hypothyroidism.