Previous studies have indicated that the oral consumption of Bb probiotics significantly decreased the levels of triglycerides, alkaline phosphatase, low-density lipoprotein, VDR, and LPR gene expression in mouse colon cancer (Tjalsma et al., 2012; Feng et al., 2015; Yang et al., 2019; Kim et al., 2020; Vacante et al., 2020). The gene discussed is VDR; the disease is colonic neoplasm.