A disturbed Proteobacteria microbiota has been previously associated with psoriasis (Alekseyenko et al., 2013), eczema (Zeeuwen et al., 2017) and diabetic foot ulcers (Gardner et al., 2013), with greater Proteobacteria diversity correlated with T-helper1, interleukin-10 and anti-inflammatory immune responses that were protective against allergic inflammation (Hanski et al., 2012; Fyhrquist et al., 2014). Here, IL10 is linked to diabetic foot.