In an ovarian cancer model, mice harboring tumors deficient in ARID1A, a component of the switch/sucrose non-fermentable (SWI/SNF) chromatin remodeling complex, exhibited increased TMB and impaired mismatch repair capacity, and notably demonstrated reduced tumor growth and improved survival in response to anti-PD-1 therapy compared to those with control tumors (72). Here, PDCD1 is linked to neoplasm.