For example, engagement in regular exercise can increase BDNF-release, hippocampal volume, and resilience to neuropathology and cognitive impairment (Arida and Teixeira-Machado, 2021), and replacing some of an ultra-processed diet with less processed foods is estimated to reverse the risk of neurodegeneration associated with its intake (Li et al., 2022). This evidence concerns the gene BDNF and Cognitive impairment.