GPT and cryohydrocytosis: Table 3 shows that after treatment of CHC patients (group II and group III) there were no significant differences compared to the healthy control group (group I) regarding ALT, AST, total bilirubin, direct bilirubin, INR, prothrombin time, serum creatinine level (p = 0.612, p = 0.873, p = 0.651, p = 0.069, p = 0.536, p = 0.346, respectively), while there were significant differences regarding albumin, hemoglobin, cholesterol, LDL, HDL, MDA, and melatonin (p < 0.001, p =0.004, p < 0.001, p = 0.026, p < 0.001, p < 0.001, p < 0.001, respectively).