GPT and cryohydrocytosis: Table 2 shows that CHC patients (pre-treatment, group II and group III) had significantly higher ALT, AST, GGT, and MDA than the control group (group I) (p < 0.001, p = 0.009, p < 0.001, p < 0.001, respectively), but significantly lower albumin, hemoglobin, cholesterol, LDL, HDL, and melatonin (p < 0.001, p = 0.001, p < 0.001, p = 0.004, p = 0.014, p < 0.001, p < 0.001 respectively).