Another scRNA-seq study revealed that ectopic expression of intercellular adhesion molecule-1 (ICAM1) in liver kinase B1 (LKB1) -deficient tumors increases the homing and activation of adoptively transferred SIINFEKL-specific CD8+ T cells, reactivates tumor-effector cell interactions and resensitizes tumors to ICB [159]. The gene discussed is STK11; the disease is neoplasm.