Based on our RNA-sequencing data, the Hallmark GSEA results indicated that BLACAT3 knockdown enriched EMT, IL6/JAK/STAT3, inflammatory response, KRAS, and TNFA/NF-κB pro-inflammatory signaling along with other gene sets related to tumor angiogenesis and metastasis (Fig. 8H). This evidence concerns the gene IL6 and neoplasm.