NCF2/p67phox expression has been reported to be upregulated in clear cell renal cell carcinoma (ccRCC) [23], urothelial carcinoma [20], malignant glioma [24, 25], hepatocellular carcinoma [26, 27] and colorectal carcinoma [28], and associated with poor prognosis. This evidence concerns the gene NCF2 and urothelial carcinoma.