Interestingly, we observed elevated frequencies of IFNγ+IL-5+, IFNγ+IL-9+, and IFNγ+IL-13+ double-producing Tc cells, supporting type-2 skewing of IFNγ+ Tc1 cells in asthma (Fig. 1B, Supplementary Fig. 1E). The gene discussed is IFNG; the disease is asthma.