Consistent with our in vitro discoveries, tumours formed in the C1galt1f/f/Erb mice were seen to express higher amounts of TF (12.8 ± 4.8% staining) and low levels of Tn (<1% staining) structures than those in ME C1galt1-/-/Erb mice (Fig. 7c, Fig. S2). The gene discussed is ESR2; the disease is neoplasm.