CD36 and neoplasm: Consistence with the in situ tumorigenic lung metastasis model (Fig. 7H), when compared CD36 expression with that in the normal lung cells of ShCD36-NCD mice, CD36 expression level was higher in the loosely arranged A549-Scramble tumor cells in lungs of NCD-fed mice, in A549-Scramble tumor marginal cells that were invading the surroundings in lungs of HFD-fed mice, and in A549-ShCD36 neoplasia cells in lungs of HFD-fed mice (Fig. 8C), indicating that CD36 high expression was accompanied with the development of the metastatic tumor.