To better understand the consequences of GREB1 OE in MNA+ NB, we used a bioinformatic approach to cross-reference multiple publicly available or in-house generated RNA-seq, and proteomic datasets, including transcriptomes of two large NB tumor cohorts, RNA-seq of NB cells ± GREB1 depletion or MYCN depletion, and an integrated translatomic and proteomic screen for suppressors of anoikis in transformed cells. The gene discussed is MYCN; the disease is neuroblastoma.