In addition, one of the inputs on which the model was trained (aside from readily available population statistics such as infant mortality rate, doctors per capita or GDP) was an estimate of the proportion of individuals in a particular region and at a particular time who were receiving a “minimal” versus a more than minimal (“non-minimal”) level of care (minimal care is defined as a simple insulin regimen with minimal or no self-blood glucose monitoring, HbA1c testing, and diabetes education) [2, 7]). The gene discussed is INS; the disease is diabetes mellitus.