We analyzed the expression of receptors for IFN-γ and TNF-α on the surface of leukemia cells by quantifying the antigen binding capacity for TNF-α receptor type 1 (TNFR-1), TNF-α receptor type 2 (TNFR-2), IFN-γ receptor (INFGR) and membrane bound TNF-α. This evidence concerns the gene TNFRSF1A and leukemia.