In this study, we used data from public datasets, including the Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO), the Human Protein Atlas (HPA), the Chinese Glioma Genome Atlas (CGGA), and the Clinical Proteomic Tumor Analysis Consortium (CPTAC) to investigate the association between SLC31A1 gene expression and clinical outcomes in glioma patients. This evidence concerns the gene SLC31A1 and central nervous system cancer.