In addition, three novel correlations were indicated in this study, namely the correlation of PDE11A and PALB2 with lung cancer, and that of SLX4 with liver cancer, while the rest of genes identified in this study have known correlations with their corresponding cancer types (Table 1) according to Human Gene Mutation Database (HGMD) and previous studies.6, 16, 17, 18, 19, 20, 21, 22. The gene discussed is SLX4; the disease is cancer.