NR3C2 and Disorder of lipid metabolism: Our (Habibi et al. 2022, Hulse et al. 2022) and other (Ramirez et al. 2013) preclinical studies further demonstrated MR antagonisms prevented Western diet- or palmitic acid-induced increases in FFA uptake, ectopic lipid droplet accumulation, and lipid metabolic disorders in liver, skeletal muscle, and heart.