To further explore the therapeutic potential of APPI‐4M‐HSA in a physiologically relevant environment, we used an orthotopic model of human ovarian cancer comprising OVCAR‐3‐LUC tumor xenografts (express KLK6) in immunodeficient mice [48], where OVCAR‐3 cells are human epithelial ovary adenocarcinoma cells originally isolated from a malignant effusion. Here, ALB is linked to ovarian carcinoma.