In non-tumor-lesioned intestinal epithelial cells, butyric acid is transported via transponders located on the apical side of colonocytes—monocarboxylate transporter 1 (MCT1), sodium-coupled monocarboxylate transporter 1 (SMCT1), breast cancer resistance protein (BCRP), and the SCFA/HCO3 exchange (Cuff et al., 2005; Thibault et al., 2007). Here, SLC16A1 is linked to neoplasm.