ADCY8 and diabetes mellitus: Speculatively, eight potential active metabolites, including kaempferol, quercetin, oleanolic acid, ursolic acid, loganin, geniposide, morroniside, cornuside, were implied as key bioactive constituents, EGFR, AKT1, ADCY2, ADCY3, ADCY8, ADCY9, and GCK were possible to be the core targets which played important roles in CF against diabetes.