However, another study investigated the effect of nanocurcumin on the incidence of AF, and markers of inflammation and oxidative stress level after coronary artery bypass graft surgery, finding that curcumin treatment did not significantly improve the incidence of AF, and the levels of C-reactive protein (CRP), MDA and GSH levels were not significantly changed evidently (81). This evidence concerns the gene CRP and atrial fibrillation.