An experiment found that plasma levels of IL-17A, IL-1β, IL-6, and TGF-β1 were significantly reduced in the curcumin-treated group, and curcumin significantly shortened the duration of AF and significantly inhibited left atrial fibrosis, its bioinformatics analysis indicated that the IL-17 signaling pathway was the key to curcumin treatment of AF (80). The gene discussed is IL17A; the disease is atrial fibrillation.