Furthermore, CCL2 triggered the transcription of ZC3H12A, which upregulated K63‐linked deubiquitination and K48‐linked auto‐ubiquitination of TRAF6/3 to inhibit NF‐κB signalling, thereby reducing M1 TAMs in the TME of HER2‐positive GC.16 The gene discussed is CCL2; the disease is gastric cancer.