Given that (i) OTUB1 stabilizes p53,27, 45 (ii) MYC can also be stabilized by OTUB142 and (iii) p53 is a tumour‐suppressing protein while MYC is an oncoprotein,43, 44 the role of OTUB1 in breast cancer remains elusive. This evidence concerns the gene OTUB1 and breast cancer.