Our result illuminated that TRPM2 was a closely related factor to most immune cells based on the correlation analyses of immune cell markers, particularly to the T cell, B cell, monocyte, tumor-associated macrophage, M2 macrophage, dendritic cell, Th1 cell, Th2 cell, Tfh cell, Treg cell, and T cell exhaustion (Table 2). Here, TRPM2 is linked to neoplasm.