Xiong et al. showed that the Pt (IV) precursor was able to stably bind to albumin with the aid of lecithin, while the encapsulation of macrophage membranes further enhanced the ability of albumin nanoparticles to actively aggregate at the tumor site and effectively promoted the cellular internalization of drugs, where Pt(IV) precursor was decomposed into toxic Pt(II) drugs under cytoplasmic reduction [67]. The gene discussed is ALB; the disease is neoplasm.