The results demonstrated that the ACSL1 expression exhibited a notable correlation with the expression of m6A writers (ZC3H13, WTAP, VIRMA, RBM15, METTL3, and METTL14), m6A readers (YTHDF1, YTHDF2, YTHDF3, YTHDC1, YTHDC2, RBMX, HNRNPC, and HNRNPA2B1), and m6A erasers (FTO and ALKBH5) (Fig. 4A, P < 0.05) in TCGA ccRCC data sets. The gene discussed is YTHDC1; the disease is nonpapillary renal cell carcinoma.