PMEL and breast cancer: Malignant melanoma expressed HMB45, MelanA, and S-100 (Fig. 2); small cell lung cancer expressed TTF-1, CD56, and CgA (Fig. 3); hepatocellular carcinoma expressed GPC-3, hepatocyte, and Sall4; breast cancer expressed ER, PR, Her-2, and GCDFP-15.