TNF and rheumatoid arthritis: In order to comprehend the impact of biologic treatment on various subtypes of rheumatoid arthritis (RA), we analyzed four published datasets of RA patients who underwent treatment with Infliximab (GSE58795) (p > 0.05), anti-TNF (GSE15258) (p > 0.05), rituximab (GSE37107) (p > 0.05), methotrexate/abatacept (GSE68215) (p = 0.001).