For example, haemoglobin (HGB) and red blood cells (RBC) reflect the status of blood operation, total cholesterol (TC) and triglycerides (TG) reflect the level of lipid metabolism, alanine transaminase (ALT) and aspartate transaminase (AST) reflect liver function, and body mass index (BMI) and waist-to-hip ratio (WHR) can be directly measured and show obesity. This evidence concerns the gene GPT and obesity due to melanocortin 4 receptor deficiency.