In addition to recurrent mutations in PRPF8, TP53, EIF6, RPL5 and RPL22, we observed mutations in DNMT3A, ASXL1, TET2 and RUNX1 associated with clonal haematopoiesis (CH), consistent with the study by Kennedy et al.18. The gene discussed is RPL22; the disease is cyclic hematopoiesis.