To test our hypothesis that FAP-CAR T cells can enhance the trafficking, infiltration, and functionality of subsequently administered Meso-CAR T cells, CD45.2 C57BL/6 mice were utilized as donors to produce EGFP-tagged MigR control, Meso-CAR, and FAP-CAR T cells, and these T cells were adoptively transferred via intravenous injection into CD45.1 C57BL/6 mCerulean labelled PDAC tumor-bearing hosts. This evidence concerns the gene CXCR3 and neoplasm.