PKP2 and ocular melanoma: Conversely, PKP2 in OM (but not in SC) adipose tissue was associated with the expression levels of depot-specific37 thermogenic/beige-related genes such as NRG438,39 and TMEM2640 (Fig. S2i), which was in agreement with the enrichment revealed previously in the SVC fraction of OM fat samples38, and mostly related to the ontogenetic presence of mesothelial cells within this fat depot41.