Note that co-treatment of TUG1 ASO and three DNA-damaging agents with distinct modes-of-action (cisplatin, Temozolomide (TMZ) and CPT) showed synergistic induction of apoptosis and suppression of the growth of cancer cells including glioblastoma (Supplementary Fig. 9a–d). This evidence concerns the gene TUG1 and glioblastoma.