Eight women had PRES features. The most specific parameters for predicting PRES were age (<24 years), platelet count (<0.69 lacs/mm3), serum ALT (>129 IU/L) and AST (>55 IU/L), total bilirubin (>1.3 mg/dL), low haemoglobin (<8.7 g/dL) and presence of seizures. The most sensitive predicting parameters were serum uric acid > 5.2 mg/dL, SBP > 164 mm Hg, DBP > 100 mmHg and serum creatinine > 0.8 mg/dL. The gene discussed is GPT; the disease is Posterior Leukoencephalopathy Syndrome.