To examine the function of Daam2 phosphorylation via CK2α in a mouse model of demyelination that mimics MS (32), we injected 2% lysolecithin with AAV–MBP–CK2α and –control virus in the corpus callosum of E-mutant and WT brains, respectively (Fig. 6A). This evidence concerns the gene DAAM2 and myeloid sarcoma.