ID1 and esophageal squamous cell carcinoma: Through our study, we demonstrated that TCF3 modulated the stemness of ESCC by regulating ID1, and also demonstrated that the sensitivity of KYSE-150 and TE-1 to the chemotherapeutic drug cisplatin, which is one of the most commonly used chemotherapeutic drugs for treating esophageal cancer, was increased after knockdown of TCF3 or ID1 by siRNA.