Using this technology, we indeed detected EGFR receptor expression on the DRG neurons of the mice, and EGFR expression was significantly greater in the DRG neurons of TPAC mice (133.2% ± 14.0%), when compared to the oncogenic Kras-based KC mice (p48-Cre;LSL-KrasG12D; 100% ± 15.8%), which might explain the receptivity of TPAC-derived DRG fro TGF-α from cancer cells (Supplemental Figure 9, A and B). This evidence concerns the gene CALCA and cancer.